| Physical and Chemical Properties | Crystallized from ether-petroleum ether, melting point 99~101 ℃. Melting at about 50 ℃. Senkoman hydrochloride (Centchroman Hydrochloride):C30H35NO3?HCl. [51023-56-4]. White crystal, melting point 165~166 ℃. UV maximum absorption (methanol):232(ε3701),278nm. pKa2.1. Soluble in 10 parts chloroform, 20 parts acetone, 60 parts 95% ethanol and 20 parts methanol. Several insoluble in water, isobutanol, 0.1mol/L hydrochloric acid or 0.1mol/L sodium hydroxide. Acute toxic LD50 mice (mg/kg):400 intraperitoneal injection. |
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